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الرسالة: [QUOTE="apostle.paul, post: 3406041, member: 85886"] [COLOR="Black"][FONT="Arial Black"][SIZE="5"][FONT=Book Antiqua][B]اخيرا هو جايبلى مقالة من جرنال طبى وانا هجبلك مقال من جرنال طبى وجدوا ان الجرعة المتوسطة لتناول الكحوليات ليها تاثير ايجابى على العظام " ظاهرة غير مفسرة " [/B][/FONT] [LEFT][B][FONT=Century Gothic]the most important finding of this study was [U][COLOR=Red]a significant positive effect of moderate alcohol consumption on BMD[/COLOR][/U]. This effect was observed with an alcohol intake >28.6 but ≤57.2 g/wk, an intake lower than reported in previous studies ([URL="http://ajcn.nutrition.org/content/72/5/1073.full#ref-6"]6[/URL]). [U][COLOR=Red]A notable aspect of this study was an attempt to explain the mechanism of alcohol's effects on bone ****bolism. Moderate alcohol consumption was shown to decrease bone remodeling, as evidenced by a reduction in bone resorption markers[/COLOR][/U] (serum osteocalcin and parathyroid hormone and urinary [I]N[/I]-telopeptides). After adjustment for age at menopause, a further explanation for the increase in BMD was elevated serum calcitonin and estrogen concentrations, which were stimulated by alcohol [/FONT][/B][LEFT][B][FONT=Century Gothic]In summary, Rapuri et al not only showed elegantly that moderate alcohol consumption has positive effects on BMD in elderly women, but also provided evidence that these effects are mediated, at least in part, by a decrease in bone remodeling. However, w[U][COLOR=Red]e remain unable to explain why only moderate doses of alcohol have been shown to have a significant positive effect on bone density.[/COLOR][/U] This article should encourage further investigations of the pathogenesis of alcohol-related bone injury; until then it would be premature to recommend alcohol use in the prevention of osteoporotic bone disease [/FONT][/B][RIGHT][FONT=Century Gothic][B][URL="http://ajcn.nutrition.org/content/72/5/1073.full"]رابط المقال[/URL] [/B][/FONT][/RIGHT] [/LEFT] [/LEFT][/SIZE][/FONT][/COLOR] [/QUOTE]

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